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Yet another reason for the drugs not to work as intended is the consumption of a high-fat meal before or along with taking the drug. The fat in such a meal can decrease absorption of the medicine from the gastrointestinal tract. You should check with your doctor immediately if any of these side effects occur when taking vardenafil:

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repliesAnalysis of the safety database from controlled clinical trials showed no apparent difference in adverse reactions in patients taking VIAGRA with and without anti-hypertensive medication. This analysis was performed retrospectively, and was not powered to detect any pre-specified difference in adverse reactions.