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The primary efficacy endpoint in the two studies that evaluated the effect of Cialis for the signs and symptoms of BPH was the International Prostate Symptom Score (IPSS), a four week recall questionnaire that was administered at the beginning and end of a placebo run-in period and subsequently at follow-up visits after randomization. The IPSS assesses the severity of irritative (frequency, urgency, nocturia) and obstructive symptoms (incomplete emptying, stopping and starting, weak stream, and pushing or straining), with scores ranging from 0 to 35; higher numeric scores representing greater severity. Maximum urinary flow rate (Qmax), an objective measure of urine flow, was assessed as a secondary efficacy endpoint in Study J and as a safety endpoint in Study K. mxman youtube Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or saquinavir) or erythromycin. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [see Drug Interactions (7.4) and Clinical Pharmacology (12.3)].CIALIS 10 mg tablets are light yellow, film coated, almond shaped tablets, marked "C10" on one side.“I think it’s a disaster. It’s unsafe and it doesn’t work. That is all a drug is supposed to do,” Leonore Tiefer, clinical associate professor of psychiatry at NYU School of Medicine told TIME.

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In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including Cialis) reported a sudden decrease or loss of vision in one or both eyes. It is not possible to determine whether these events are related directly to these medicines, to other factors such as high blood pressure or diabetes, or to a combination of these. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including Cialis, and call a healthcare provider right away.Some form of sexual stimulation is needed for an erection to happen with Cialis.Trial in Patients with ED after Radical Prostatectomy