Hepatic levitra cialis Co-administration of erythromycin, a moderate CYP3A4 inhibitor, resulted in a 160% and 182% increases in sildenafil Cmax and AUC, respectively. Co-administration of saquinavir, a strong CYP3A4 inhibitor, resulted in 140% and 210% increases in sildenafil Cmax and AUC, respectively. Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir. A starting dose of 25 mg of Viagra should be considered in patients taking erythromycin or strong CYP3A4 inhibitors (such as saquinavir, ketoconazole, itraconazole) [see Dosage and Administration (2.4), Clinical Pharmacology (12.3)].
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how does levitra work Patients with liver disease should follow their doctor's advice. Once-a-day dosing of CIALIS is not recommended in patients with severe hepatic impairment.
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83491125 NDC 0173-0830-13 viagra professional erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis)VARDENAFIL HYDROCHLORIDE TRIHYDRATE (VARDENAFIL) VARDENAFIL 5 mgIn volunteers with mild hepatic impairment (Child-Pugh A), the Cmax and AUC following a 10 mg vardenafil dose were increased by 22% and 17%, respectively, compared to healthy control subjects. No dosage adjustment is necessary in patients with mild hepatic impairment.
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